Host-Pathogen Interaction Laboratory
© 2015 - 2016 Uzonna (Created by F. Khadem)
2015 1 . Regulation    of    Immunity    to    cutaneous    Leishmaniasis    by    CD3+CD4-CD8-    (double    negative)    T    cells. Canadian   Society   for   Immunology   Guest   Society   Symposium,   American   Association   of   Immunologist Annual General Meeting, New Orleans, May 8-12, 2015. 2 . Regulation   sepsis   and   septic   shock   by   regulatory   T   cells.   Critical   Care   Research   in   Progress   Rounds, Health Sciences Centre, Winnipeg. May 28, 2015. 3 . MHC-restricted   double   negative   T   cells   contribute   to   optimal   anti-Leishmania   immunity.   PIIN   Satellite Symposium, Annual Canadian Society for Immunology Conference, Winnipeg June 4-7, 2015. 4 . Identification    of    candidate    vaccines    against    infectious    agents    by    reverse    immunology.    Invited presentation, Emergent Biosolutions, Winnipeg MB. Feb 4, 2015. 5 . Use   of   combinatorial   proteomics   and   cellular   immunology   to   identify   immunogenic   peptides   and   their specific   T   cells   at   clonal   level.   Manitoba   Centre   for   Proteomics   &   Systems   Biology   Seminar,   University   of Manitoba. March 25, 2015.
2014 1 . Reverse     Immunology     and     Systems     Biology:     a     combination     approach     that     overcomes     vaccine development   hurdles   against   an   important   human   parasitic   disease.   Edge   of   Science   and   Medicine Seminar Series, Faculty of Medicine, University of Manitoba. March 17, 2014. 2 . Reverse   Immunology:   a   cool   approach   to   identify   potentially   immunogenic   and   protective   antigens   for vaccine   development.   Edge   of   Science   and   Medicine   Seminar   Series,   Faculty   of   Medicine,   University   of Manitoba. March 17, 2014 3 . Publish to Flourish: Department of Medical Microbiology, University of Manitoba March 19, 2014. 4 . Novel   approach   for   identification   of   an   efficacious   vaccine   against   a   parasitic   disease.   R.G.E.   Murray Seminar    Series,    Department    of    Microbiology    and    Immunology,    Schulich    School    of    Medicine    and Dentistry, Western University, ON Canada March 27, 2014.
2013 1 . Identification   of   efficacious   vaccine   against   a   parasitic   disease   by   reverse   immunology.   Biomedical Research Centre, University of British Columbia March 15, 2013.
2012 1 . Finding Vaccines for a Deadly Parasitic Disease. Third Medical Military University, Chongqing China October 2012. 2 . Identification of Immunogenic and Protective Epitopes using Reverse Immunology. World Immunology Congress, Beijing October, 2012 3 . Designing a Vaccine for Parasitic Disease Using Reverse Immunology. Seattle BioMed Research Institute, Seattle May 10, 2012
2011 1. Vaccines and vaccination for parasitic diseases: myth, mirage or reality? Department of Parasitology, Faculty of Veterinary Medicine, University of Nigeria. August 3, 2011.
2010 1 . Regulation   of   secondary   anti-Leishmania   immunity   by   the   phosphoinositide   3   kinase.   International   Congress   of   Parasitology,   Melbourne,   August 17, 2010. 2 . Finding a vaccine for a deadly parasitic disease. Frontiers of Biochemical Science Seminar Series, University of Winnipeg November 10, 2010. 3 . Persistent   parasites   and   anti-Leishmania   immunity:   implications   for   vaccine   designs   and   vaccination   strategies.   Department   of   Microbiology   and Immunology Guest Speaker Series, McGill University. October 21, 2010. Department of Pharmacology, University of Manitoba May, 2010. 4 . Genetically   modified   live-attenuated   parasites   as   alternative   vaccine   candidates   for   effective   vaccination   against   cutaneous   leishmaniasis.   Guest speaker, International Primate Research Center, Nairobi, Kenya, October 14, 2010. 5 . Regulation   of   Immunity   to   protozoan   parasites   by   the   Phosphoinositide   3   kinase   (PI3K).   Department   of   Pharmacology,   University   of   Manitoba May, 2010 6 . Generation,   maintenance   and   loss   of   established   immunity:   lessons   fro   an   intracellular   protozoan   infection.   Department   of   Medical   Microbiology and Immunology, University of Alberta April 8, 2010.
Before 2010 1 . Regulation   of   primary   and   secondary   (memory)   immunity   to   Leishmania   major.   Immunology   of   Infectious   Diseases   Satellite   Meeting,   University   of Manitoba September 10, 2009. 2 . Modulation   of   host   immunity   by   Berenil:   a   trypanocidal   agent.   Hot   topics   in   Immunology,   Department   of   Medical   Microbiology   University   of Manitoba April 20, 2009 3 . Regulation    of    immunity    to    protozoa:    implications    for    vaccine    designs    and    vaccination    strategies    Dalian    Department    of    Bioscience    and Biotechnology, Dalian University of Technology, Dalian, China October 29, 2008. 4 . The   role   of   Phosphoinositide   3   kinase   (PI3K)   in   regulating   immunity   to   intracellular   pathogens.   Third   Military   Medical   University   Chongqing,   China October 22, 2008 5 . Phosphoinositide   3   kinase   (PI3K)   regulates   immunity   to   intracellular   pathogen   Department   of   Medical   Microbiology   University   of   Manitoba   October 13, 2008 6 . Vaccine designs and vaccination strategies against parasitic disease. National Hospital Abuja, Nigeria August 5, 2008 7 . Regulation   of   Immunity   to   intracellular   pathogens:   Lessons   from   mouse   models   of   protozoan   infections.   National   Veterinary   Research   Institute, Vom Nigeria August 6, 2008 8 . Current   understanding   of   pathogenesis   of   African   trypanosomiasis:   learning   from   the   studies   of   murine   experimental   trypanosomiasis.   University of Nigeria, Nsukka July 29, 2008. 9 . Phosphoinositide 3 kinase (PI3K): more roles than just in cancer and inflammation. Manitoba Institute of Cell Biology June 12, 2008 1 0 . Factors that regulate the induction of anti-Leishmania immunity in mice. Institute of Parasitology, McGill University, May 5, 2008. 1 1 . Regulation   of   primary   and   secondary   (memory)   immunity   in   cutaneous   leishmaniasis.   Center   for   Immunology,   Department   of   Microbiology   and Immunology, University of Minnesota, St Paul Minneapolis, April 21, 2008 1 2 . Persistent   parasites   and   maintenance   of   anti-Leishmania   immunity:   implications   for   vaccine   designs   and   vaccination   strategy   against   cutaneous leishmaniasis. WHO-TDR sponsored workshop on Leishmaniasis, Pasteur Institute, Tehran, Iran Feb 29-March 5, 2008. 1 3 . Regulation   of   anti-Leishmania   immunity:   Does   strong   immunity   correlate   to   better   resistance?   Department   of   Microbiology   and   Immunology, University of Saskatchewan, January 18, 2008. 1 4 . Strategies   for   Writing   Successful   Tri-council   Grant.   Presented   to   the   Western   Regional   Training   Center   for   Health   Research   Services   Fall   Institute, Place Riel Winnipeg November 18-19, 2007. 1 5 . Immunity    to    Leishmania    major:    stronger    response    better    resistance?    CIHR    Group    Leishmania    Satellite    Meeting,    Centre    de    Recherche    en Infectiologie de l’Universite Laval Quebec City, Quebec Canada October 22-24, 2007. 1 6 . Complex   host-parasite   interactions   regulate   Immunity   to   Leishmania   major   in   mice.   Parasitology   Research   Seminars,   University   of   Pennsylvania. April 16, 2007. 1 7 . *The   development   of   T   cell   memory   in   parasitic   infections:   implications   for   vaccine   designs   and   vaccination   strategies.   Department   Immunology, University of Manitoba. October 13, 2005 1 8 . Development   and   maintenance   of   CD4+   T   cell   memory   during   Leishmania   major   infection.   Departments   of   Biology   and   Veterinary   Science,   South Dakota State University, Brookings SD. April 29, 2005. 1 9 . Maintenance and loss of established immunity to Leishmania major. Immunology Research Group, University of Saskatchewan. May 16, 2004. 2 0 . Resistance    to    Leishmania    major:    modulation    of    CD4+    T    helper    cell    response    by    CD8+    T    cells.    Parasitology    Research    Group    Seminar    series, University of Pennsylvania. March 15, 2004 2 1 . Regulation   of   CD4+   T   helper   cell   response   by   parasite   dose   and   CD8+   T   cells   in   mice   infected   with   Leishmania   major.   Department   of   Microbiology and Immunology, University of Missouri. April 10, 2003. 2 2 . Immunity to Leishmania major: paradigm drifts and shifts. Department of Immunology, University of Manitoba. April 5, 2003. 2 3 . Immune   response   to   glycophosphate   conjugate   deficient   Leishmania   major.   Department   of   Biology,   Howard   University   Washington   DC.   March 2003. 2 4 . Glycophosphate   conjugate   deficient   Leishmania   major:   possible   live-attenuated   vaccine   candidate   against   cutaneous   leishmaniasis.   Department   of Biology, State University of New York Brockport, March 2003. 2 5 . CD8+   T   cell-mediated   immunity   to   L.   major:   influence   of   parasite   dose   and   route   of   infection.   Dept   of   Microbiology   and   Immunology   Seminar   Series University of Saskatchewan, Thursday November 28, 2002. 2 6 . Enhancing   vaccine-induced   local   and   systemic   immunity   against   Mycobacterium   paratuberculosis   in   cattle.   Veterinary   Microbiology   Seminar   Series, University of Saskatchewan, Friday November 29, 2002. 2 7 . Delayed   onset   of   lesion   development   and   progression   in   Leishmania   mexicana-infected   C57BL/6   mice   is   mediated   by   TNF-a-dependent   inhibition of   parasite   replication   in   infected   macrophages   and   dendritic   cells.   Host-Pathogen   Interaction   Workshop,   16th   Spring   Meeting   of   the   Canadian Society for Immunology, Collingwood Ontario, April 5-8, 2002 2 8 . Low   dose   neonatal   oral   immunization   with   heat-killed   Mycobacterium   paratuberculosis   protects   calves   against   high   dose   virulent   challenge.   7th International Colloquium on Paratuberculosis, Bilbao Spain, 11-14th June 2002. 2 9 . Immune   elimination   of   Leishmania   major   in   mice:   implications   for   vaccination,   immunological   memory   and   reactivation   disease.   Parasitology Seminar Series, Dept of Pathobiology, University of Pennsylvania Monday September 25, 2000. 3 0 . Generation   of   different   pathophysiological   disease   states   in   mice   infected   with   L.   major:   implications   for   vaccination,   memory   and   reactivation disease. Dept of Microbiology and Immunology Seminar Series University of Saskatchewan, Thursday September 7, 2000. 3 1 . Requirement   of   antigen   persistence   for   maintenance   of   immunological   memory   to   a   protozoan   parasite   Leishmania   major.   Fourth   International Congress of Federation of African Immunological Societies Yaounde Cameroon, February 14-18, 2000 3 2 . Immune   elimination   of   Leishmania   major   in   mice:   implications   for   vaccination,   immunological   memory   and   reactivation   disease.   Parasitology Seminar Series, Dept of Pathobiology, University of Pennsylvania Monday September 25, 2000. 3 3 . Generation   of   different   pathophysiological   disease   states   in   mice   infected   with   L.   major:   implications   for   vaccination,   memory   and   reactivation disease. Dept of Microbiology and Immunology Seminar Series University of Saskatchewan, Thursday September 7, 2000. 3 4 . Requirement   of   antigen   persistence   for   maintenance   of   immunological   memory   to   a   protozoan   parasite   Leishmania   major.   Fourth   International Congress of Federation of African Immunological Societies Yaounde Cameroon, February 14-18, 2000 3 5 . Immunoregulation   in   experimental   African   trypanosomiasis:   adherent   Thy1.2+   CD3+   CD4-8-   TCR      NK1.1-   cells   produce   IL-10   and   IFN-   and mediate trypanosome-induced immunosuppression. 13th Annual Spring Meeting of Canadian Soc. for Immunology, Lake Louise, AB, March 1999. 3 6 . Experimental    African    trypanosomiasis:    a    novel    adherent    splenic    lymphocyte    secretes    IL-10    and    IFN-    and    mediates    trypanosome-elicited immunosuppression. 3rd Annual Immunoparasitology Meeting, Woods Hole, MA. May 1-5 1999. 3 7 . Role    of    interferon    gamma    in    the    suppression    of    spleen    cell    proliferative    response.    First    international    Veterinary    Vaccines    and    Diagnostics Conference, Madison, Wisconsin, July 23-31, 1997 3 8 . Experimental    African    trypanosomiasis:    Involvement    of    interleukin    10    and    interferon    gamma    in    the    suppression    of    spleen    cell    proliferative response. Proc. 11th Spring Meet. Canadian Soc. For Immunology, Lake Louise, Alberta, March 1997.
Invited Lectures / Presentations
Publications Publications R G